Science is what makes the difference
10+ years research studies in collaboration with 38 researchers and experts led to the publication of two scientific articles presenting data and numbers from the field.
Field experimentation
Data-driven results measured in the field
Honey Production Increase
Trials conducted in Spain2, Moldova1, and Greece2 between 2018 and 2023, with a total of 130 hives tested. The equalized hives were divided into two randomly selected groups: one fed with a Mo-based complex in the sugar syrup, and a control group receiving pure sugar syrup.
Figure 1. Increase in honey production in Molybdenum complex-treated groups compared to control groups, expressed in kg. The * indicates statistically significant values (p < 0.05). The data points measured as surface were transformed to kg. The whole apiary at the beginning of the season was considered. Sources: 1Fuior et al., 2025, 2Benito-Murcia et al. 2025.
Study details
| Country | Moldava | Greece | Spain |
| Years | 2018 | 2022 | 2023 |
| Subspecies | Carnica | Macedonica | Iberica |
| Laboratory | Institute of Zoology | Hellenic Institute of Agriculture | Extremadura University |
Supervised by:
- Dr. Fani Hatjina
- Prof. Risco Perez
- Prof. Ion Toderas
- Prof. Sébastien Floquet
- Dr. Maria Benito Murcia
Impact on winter survival
Trials conducted over two winter seasons (2023–2025) across six apiaries in France2 and Spain2, with a total of 247 hives. Hives were divided into two homogeneous groups: one fed with Mo complex in sugar syrup and a control fed with pure sugar syrup.
Figure 2. Winter losses measured in each apiary in the groups fed with the Molybdenum complex, compared to the control group. The % corresponds to the part of the apiary that did not survive the winter. The average reduction across apiaries was -44% (p=0.029). Source: 2Benito-Murcia et al. 2025
Study details
| Country | France | Spain | Spain |
| Years | 2018 | 2023 | 2024 |
| Subspecies | Buckfast | Iberica | Iberica |
| Laboratory | Apinov | Extremadura University | Extremadura University |
Supervised by:
- Dr. Benjamin Poirot
- Prof. David Risco Perez
- Dr. Maria Benito Murcia
- Dr. Clémence Riva,
Highest standards, certified by the authorities
Canada
The molybdenum compound has been approved as a Veterinary Health Product by Health Canada in February 2026 (NN.L9V2)
Europe
The ingredient obtained a positive opinion from EFSA (European Food Safety Authority) and is in progress for the authorisation as a zootechnical additive.
GMP+ certified
A GMP+ quality and feed safety system guarantees the highest quality standards for our production facility and across the organisation.
Safety and quality have been studied and confirmed by strict regulatory procedures in all aspects: bees, beehive products, beekeepers, and the environment.
Honey Production Increase
Trials conducted in Spain2, Moldova1, and Greece2 between 2018 and 2023, with a total of 130 hives tested. The equalized hives were divided into two randomly selected groups: one fed with a Mo-based complex in the sugar syrup, and a control group receiving pure sugar syrup.
Study details
| Country | Moldova | Greece | Spain |
| Years | 2018 | 2022 | 2023 |
| Subspecies | Carnica | Macedonica | Iberica |
| Laboratory | Institute of Zoology | Hellenic Institute of Agriculture | Extremadura University |
Supervised by
- Dr. Fani Hatjina
- Prof. Risco Perez
- Prof. Ion Toderas
- Prof. Sébastien Floquet
- Dr. Maria Benito Murcia
Impact on winter survival
Trials conducted over two winter seasons (2023–2025) across six apiaries in France2 and Spain2, with a total of 247 hives. Hives were divided into two homogeneous groups: one fed with Mo complex in sugar syrup and a control fed with pure sugar syrup.
Study details
| Country | France | Spain | Spain |
| Years | 2018 | 2023 | 2024 |
| Subspecies | Buckfast | Iberica | Iberica |
| Laboratory | Apinov | Extremadura University | Extremadura University |
Supervised by
- Dr. Benjamin Poirot
- Prof. David Risco Perez
- Dr. Maria Benito Murcia
- Dr. Clémence Riva,
Highest standards, certified by the authorities
Canada
The molybdenum compound has been approved as a Veterinary Health Product by Health Canada in February 2026 (NN.L9V2)
Europe
The ingredient obtained a positive opinion from EFSA (European Food Safety Authority) and is in progress for the authorisation as a zootechnical additive.
GMP+ certified
A GMP+ quality and feed safety system guarantees the highest quality standards for our production facility and across the organisation.
Safety and quality have been studied and confirmed by strict regulatory procedures in all aspects: bees, beehive products, beekeepers, and the environment.
International collaboration
38 researchers and beekeeping experts participated in the research. Third-party validation is what transforms beliefs into science.
Apinov, France
Faculty of Veterinary Medicine, University of Extremadura, Spain
Institute of Animal Science, Demeter, Greece
University of Versailles Saint-Quentin-en-Yvelines, France
The French National Centre for Scientific Research (CNRS), France
Tech transfer SATT Paris-Saclay
The University of Manitoba, Canada
Publications
The research is validated and published in scientific peer-reviewed journals.
Download our Whitepaper
The complete summary of the trials.
Thank you!
Our Whitepaper is heading to you! It may take a few minutes to arrive in your inbox.
Science & Evidence FAQ
Does Pep'up always work?
Of course not! Do not believe in magic. If a colony is starving due to a severe lack of flowers or is overrun by an untreated disease, one product alone cannot save it. However, with its formula precisely designed for honey bees, Pep’up gives a strong biological foundation to maximize colonies’ resilience and productivity when facing stress.
Why is it important that you tested on different subspecies across 6 countries?
Beekeeping isn’t a controlled lab experiment, it happens in the unpredictable outdoors. By testing on different subspecies of Apis Mellifera (Buckfast, Iberica, Carnica) across diverse climates and seasons, the probability that the results are universal is maximized.
What does "peer-reviewed" mean?
It means we don’t just ask you to take our word for it. Independent, anonymous scientists specialized in the field have rigorously reviewed and approved the protocols, data, and conclusions before allowing them to be published in official scientific journals.
How does this product actually help the bees?
Studies demonstrated that the complex permits the bioassimilation of molybdenum in key organs, namely the brain neurolemma and the hypopharyngeal glands. Moreover, the compound itself has antioxidant properties, which are known to improve organisms’ response to stressors.
Are the field trials truly independent?
All data presented above comes from the research studies conducted by public and private independent research centers, and were published in the scientific peer-reviewed journals.
1Fuior, A. et al. (2025). Feed supplementation with molybdenum complexes improves honey bee health.
2Benito-Murcia, M. et al. (2025). Reducing honey bee winter mortality with molybdenum supplementation: Field evidence across Europe.
The information provided on this website is, to the best of our knowledge, true and accurate. Not all products are available in all regions, nor are the associated intended uses and/or claims the same in all regions. Products must only be used in compliance with local laws and regulations, and we cannot guarantee freedom for every intended use or country.